DAPHNA JOEL

Popular Publications

The documents distributed here have been provided as a means to ensure timely dissemination of scholarly and technical work on a noncommercial basis. Copyright and all rights therein are maintained by the authors or by other copyright holders, notwithstanding that they have offered their works here electronically. It is understood that all persons copying this information will adhere to the terms and constraints invoked by these copyrights. These works may not be reposted without the explicit permission of the copyright holder. 

REFEREED ARTICLES   

82. Joel D. (2021) Uncovering and challenging the binary framework. Psychological Inquiry, 32(2): 105-106. PDF HTML
81. Rippon G., Eliot L., Genon S., Joel D. (2021) How hype and hyperbole distort the neuroscience of sex differences. PLoS Biol., 19(5): e3001253 PDF HTML
80. Saguy T., Reifen Tagar M., Joel D. (2021) The Gender-Binary Cycle: The perpetual relations between a biological-essentialist view of gender, gender ideology, and gender-labeling and sorting. Phil. Trans. R. Soc. B., 376: 20200141 PDF HTML
79. Joel D. (2021) Beyond the binary: Rethinking sex and the brain. Neuroscience and Biobehavioral Reviews, 122: 165-175. PDF HTML
78. Berman Z., Assaf Y., Tarrasch R., Joel D. (2020) Macro- and microstructural gray matter alterations in sexually assaulted women. Journal of Affective Disorders, 262: 196-204. PDF HTML
77. Alon N., Meilijson I., Joel D. (2020) Analyzing brain data by sex: Are we asking the right question? bioRxiv. PDF HTML
76. Jacobson R., Joel D. (2020) Gender identity and sexuality in an online sample of intersex-identified individuals: a descriptive study. Psychology and Sexuality. PDF HTML
75. Joel D., Garcia-Falgueras A., Swaab D. (2020) The complex relationships between sex and the brain. Neuroscientist, 26:156-169 PDF HTML
74. Shalev R., Admon, R. Berman Z. Joel D. (2020) A mosaic of sex-related structural changes in the human brain following exposure to real-life stress. Brain Structure & Function  PDF HTML
73. Fine C., Joel D., Rippon G. (2019) Eight Things You Need to Know About Sex, Gender, Brains, and Behavior: A Guide for Academics, Journalists, Parents, Gender Diversity Advocates, Social Justice Warriors, Tweeters, Facebookers, and Everyone Else. S&F Online. HTML
72. Joel D., Garcia-Falgueras A., Swaab D. (2019) The complex relationships between sex and the brain. Neuroscientist PDF HTML
71. Joel D., Persico A., Salhov M., Berman Z., Oligschläger S., Meilijson I, Averbuch A. (2018) Analysis of human brain structure reveals that the brain ‘types’ typical of males are also typical of females, and vice versa. Frontiers in Human Neuroscience, 12:399 PDF HTML
70. Jacobson R., Joel D. (2018) Self-reported gender identity and sexuality in an online sample of cisgender, transgender and gender-diverse individuals: an exploratory study. J. Sex. Res., 56:249-263 PDF HTML
69. Jacobson R., Joel D. (2018) An exploration of the relations between self-reported gender identity and sexual orientation in an online sample of cisgender individuals. Arch. Sex. Behav., 47:2407-2426. PDF HTML
68. Berman Z., Assaf Y., Tarrasch R., Joel D. (2018) Assault-related Self-Blame and its Association with PTSD in Sexually Assaulted Women: An MRI Inquiry. Social Cognitive and Affective Neuroscience. 13: 775-784. PDF HTML
67. Hyde J.S., Bigler R., Joel D., Tate C., van Anders S. (2018) The Future of Sex and Gender in Psychology: Five Challenges to the Gender Binary. Am. Psychologist. PDF
66. Fine. C., Dupre J., Joel D. (2017) Sex and Gender: Evolution, Stability, and Variability, Trends Cog. Sci., 21: 666-673. PDF
65. Rippon G., Jordan-Young R., Kaiser A., Joel D., Fine. C. (2017) Journal of neuroscience research policy on addressing sex as a biological variable: comments, clarifications, and elaborations. J. Neurosci. Res. Feb 22;Early view. Available from, DOI: 10.1002/jnr.24045.
64. Joel D. (2016) Captured in terminology: sex, sex categories, and sex differences. Feminism & Psychology, 26, 335–345. PDF
63. Joel D., McCarthy M.M. (2017) Circumspective: Incorporating Sex As a Biological Variable in Neuropsychiatric Research: Where Are We Now and Where Should We Be? Neuropsychopharmacology PDF
62. Joel D., Persico A., Hänggi J., Pool J., Berman Z. (2016) Reply to Del Guidice et al, Chekroud et al, and Rosenblatt: Do brains of females and males belong to two distinct populations? Proc Natl Acad Sci USA PDF
61. Joel D., Hänggi J.,  Pool J. (2016) Reply to Glezerman: Why differences between brains of females and brains of males do not ‘add up’ to create two types of brains. Proc Natl Acad Sci USA PDF
60. Joel D., Fausto-Sterling A. (2016) Beyond sex differences: New approaches for thinking about variation in brain structure and function. Phil. Trans. R. Soc. B., 371: 20150451 PDF  link
59. Joel D., Berman Z., Tavor I., Wexler N., Gaber O., Stein Y., Shefi N., Pool J., Urchs S., Margulies D., Liem F., Hänggi J., Jäncke L., Assaf Y. (2015) Sex beyond the genitalia: The human brain mosaic. Proc Natl Acad Sci U S A PDF
58. Goltseker, K., Yankelevitch-Yahav R., Albelda, N., & Joel D. (2015). Signal attenuation as a rat model of obsessive-compulsive disorder. Journal of Visualized Experiments, (95), e52287. doi:10.3791/52287 Link
57. Lotan D., Benhar I., Moses A.E., Rehavi M., Cunningham M., Joel D. (2014) Antibiotic Treatment Attenuates Behavioral and Neurochemical changes Induced by Exposure of Rats to Group A Streptococcal Infection. Plos One PDF
56. Joel D. and Yankelevitch-Yahav R. (2014) Reconceptualizing sex, brain and psychopathology: Interaction, interaction, interaction. Br. J. Pharmacology, 171, 4620-4635. PDF
55. Lotan D., Benhar I., Alvarez K., Mascaro-Blanco A., Cox C., Moses A.E., Frenkel D., Cunningham M., Joel D. (2014) Behavioral and neural effects of intra-striatal infusion of anti-streptococcal antibodies in rats. Brain, Behavior, and Immunity, 38:249-62 PDF
54. Joel D. (2014) Response to Nina K. Thomas and J. Scott Rutan: Is the Personal Political? And Who Benefits From Believing It Is Not? International Journal of Group Psychotherapy, 64, 83-89. PDF
53. Joel D. and Yarimi D. (2014) Consciousness-raising in a gender conflict group. International Journal of Group Psychotherapy, 64, 48-69. PDF
52. Joel D., Tarrasch R., Berman Z., Mukamel M. and Ziv E. (2014) Queering gender: studying gender identity in the normative population. Psychology and Sexuality, 5, 291-321. PDF
51. Yankelevitch-Yahav R., Joel D. (2013) Studying the role of acetylcholine in the signal attenuation rat model of obsessive-compulsive disorder. Psychopharmacology, 230, 37-48. PDF
50. Joel D. (2012) Genetic-gonadal-genitals sex (3G-sex) and the misconception of brain and gender, or, why 3G-males and 3G-females have intersex brain and intersex gender. Biology of Sex Differences. 3, 27. PDF
49. Brimberg L., Benhar I., Mascaro-Blanco A., Alvarez K.,  Lotan D., Winter C., Klein J., Moses A.E., Somnier F.E., Leckman J.F., Swedo S.E., Cunningham M.W., Joel D. (2012) Behavioral, pharmacological, and immunological abnormalities after streptococcal exposure: a novel rat model of Sydenham chorea and related neuropsychiatric disorders. Neuropsychopharmacology, 37, 2076–2087 PDF
48. Albelda N. and Joel D. (2012) Animal models of obsessive-compulsive disorder: Exploring pharmacology and neural substrates. Neuroscience & Biobehavioral Reviews, 36, 47-63. PDF
47. Albelda N. and Joel D. (2011) Current animal models of obsessive compulsive disorder: An update. Neuroscience. 211, 83-106. PDF
46. Joel D. (2011) Male or female? Brains are intersex. Frontiers in Integrative Neuroscience, 5, 57. PDF
45. Djodari-Irani A., Klein J., Banzhaf J., Joel D., Heinz A., Harnack D., Lagemann T., Juckel G., Kupsch A., Morgenstern R., Winter C. (2011) Activity modulation of the Globus pallidus and the Nucleus entopeduncularis affects compulsive checking in rats. Behavioural Brain Research, 219, 149-158. PDF
44. Klavir O, Flash S., Winter C. and Joel D. (2011) High but not low frequency stimulation of both the globus pallidus and the entopeduncular nucleus  reduces ‘compulsive’ lever-pressing in rats. Behavioural Brain Research, 216, 84-93. PDF
43. Albelda N., Bar-On N. and Joel D. (2010) The role of NMDA receptors in the signal attenuation rat model of obsessive-compulsive disorder. Psychopharmacology, 210, 13-24. PDF
42. Schilman E.A., Klavir O., Winter C., Sohr R., Joel D. (2010) The role of the striatum in compulsive behavior in intact and orbitofrontal cortex lesioned rats: possible involvement of the serotonergic system. Neuropsychopharmacology, 35, 1026-1039. PDF
41. Schonberg T., O’Doherty J.P., Joel D., Inzelberg R., Segev Y., Daw N.D. (2010) Selective impairment of prediction error signaling in human dorsolateral but not ventral striatum in Parkinson’s disease patients: evidence from a model-based fMRI study. NeuroImage. 49, 772-781 PDF
40. Mundt A., Klein J., Joel D., Heinz A., Djodari-Irani A., Harnack D., Kupsch A., Juckel G., Orawa H., Morgenstern R., Winter C. (2009) High frequency stimulation of the nucleus accumbens core and shell reduces quinpirole-induced compulsive checking in rats. Eur. J. Neurosci. 29, 2401-2412. PDF
39. Flaisher-Grinberg S., Albelda N., Gitter L., Weltman K., Arad M. and Joel D. (2009) Ovarian hormones modulate ‘compulsive’ lever-pressing in female rats. Hormones and Behavior, 55, 356-365. PDF
38. Klavir O, Flash S., Winter C. and Joel D. (2009) High frequency stimulation and pharmacological inactivation of the subthalamic nucleus reduces ‘compulsive’ lever-pressing in rats. Experimental Neurology, 215, 101-109. PDF
37. Winter C., Flash S., Klavir O., Klein J., Sohr R. and Joel D. (2008) The role of the subthalamic nucleus in ‘compulsive’ behavior in rats. Eur. J. Neurosci. 27, 1902-1911 PDF
36. Flaisher-Grinberg S., Klavir O. and Joel D. (2008) The role of 5-HT2a and 5-HT2c receptors in the signal attenuation rat model of obsessive compulsive disorder. Int. J. Neuropsychopharmacol 11, 811–825 PDF
35. Schilman E. A., Uylings H. B., Galis-de Graaf Y., Joel D., Groenewegen H. J. (2008) The orbitofrontal cortex in rats topographically projects to central parts of the caudate-putamen  complex. Neurosci. Lett. 432, 40-45 PDF
34. Winter C., Mundt A., Jalali R., Joel D., Harnack D., Morgenstern R. , Juckel G., Kupsch A. (2008) High frequency stimulation and temporary inactivation of the subthalamic nucleus reduce quinpirole induced compulsive checking behavior in rats. Experimental Neurology 210, 217-228 PDF
33. Schonberg T., Daw N., Joel D., O’Doherty J.P.  (2007) Reinforcement learning signals in the human striatum distinguish learners from non-learners during reward-based decision making. J. Neurosci. 27, 12860-12867 PDF
32. Brimberg L., Flaisher S., Schilman E. and Joel D. (2007) Strain differences in compulsive lever-pressing. Behavioural Brain Research, 179, 141-151. PDF
31.  Niv Y., Daw N.D., Joel D. and Dayan P. (2007) Tonic dopamine: Opportunity costs and the control of response vigor. Psychopharmacology, 191, 507-520. PDF
30. Niv Y., Joel D., Dayan P. (2006). A normative perspective on motivation. Trends Cog. Sci. 10, 375-381. PDF
29. Joel D., Klavir O. (2006) The effects of temporary inactivation of the orbital cortex in the signal attenuation rat model of obsessive compulsive disorder. Behavioral Neuroscience, 120, 976-83. PDF
28. Joel D. (2006) The signal attenuation rat model of obsessive-compulsive disorder: A review. Psychopharmacology, 186, 487-503. PDF
27. Joel D. (2006) Current animal models of obsessive compulsive disorder: A critical review. Progress in Neuropsychopharmacology and Biological Psychiatry, 30, 374-388. PDF
26. Tarrasch R., Goelman G., Joel D., Weiner I. (2005) Long term functional consequences of quinolinic acid striatal lesions and their alteration following an addition of a globus pallidus lesion assessed using pharmacological magnetic resonance imaging. Experimental Neurology, 196, 244-253. PDF
25. Joel D., Doljansky J., Schiller D. (2005) ‘Compulsive’ lever-pressing in rats is enhanced following lesions to the orbital cortex, but not to the basolateral nucleus of the amygdala or to the dorsal medial prefrontal cortex. Eur. J. Neurosci. 21, 2252-2262. PDF
24. Joel D., Zohar O., Afek M., Hermesh H., Lerner L., Kuperman R., Gross-Isseroff R., Weizman A. and Inzelberg R. (2005) Impaired procedural learning in obsessive compulsive disorder and Parkinson’s disease, but not in major depressive disorder. Behavioural Brain Research, 157, 253-263. PDF
23. Joel D., Doljansky J., Roz N. and Rehavi M. (2005) Role of the orbital cortex and the serotonergic system in a rat model of obsessive compulsive disorder. Neuroscience, 130, 25-36. PDF
22. Joel D., Ben-Amir E., Doljansky J. and Flaisher S. (2004) ‘Compulsive’ lever-pressing in rats is attenuated by the serotonin re-uptake inhibitors paroxetine and fluvoxamine but not by the tricyclic antidepressant desipramine or the anxiolytic diazepam. Behavioral Pharmacology, 15, 241-252. PDF
21. Ayalon L., Doron R., Weiner I. and Joel D. (2004) Amelioration of behavioral deficits in a rat model of Huntington’s disease by an excitotoxic lesion to the globus pallidus. Experimental Neurology, 186, 46-58 PDF
20. Joel D., Ayalon L., Tarrasch R., and Weiner I. (2003) Deficits induced by quinolinic acid lesion to the striatum in a position discrimination and reversal task are ameliorated by permanent and temporary lesion to the globus pallidus: A potential novel treatment in a rat model of Huntington’s disease. Movement Disorders, 18,1499-507. PDF
19.  Weiner I., Schiller D., Gaisler-Salomon I., Green A. and Joel D. (2003) A comparison of drug effects in latent inhibition and the forced swim test differentiates between the typical antipsychotic haloperidol, the atypical antipsychotics clozapine and olanzapine, and the antidepressants imipramine and paroxetine. Behavioural Pharmacology, 14, 215-222. PDF
18. Joel D. and Doljansky J. (2003) Selective alleviation of ‘compulsive’ lever-pressing in rats by D1, but not D2, blockade: Possible implications for the involvement of D1 receptors in obsessive compulsive disorder. Neuropsychopharmacology, 28, 77-85. PDF
17. Niv Y., Joel D., Meilijson I. and Ruppin E. (2002) Evolution of reinforcement learning in bees: A simple explanation for complex foraging behaviors. Adaptive Behavior, 10, 5-24. PDF
16. Joel D., Niv Y. and Ruppin E. (2002) Actor-critic models of the basal ganglia: New anatomical and computational perspectives. Neural Networks, 15, 535-547. PDF
15. Joel D. (2001) The open interconnected model of basal ganglia-thalamocortical circuitry and its relevance to the clinical syndrome of Huntington’s disease. Movement Disorders, 16, 407-23. PDF
14. Joel D., Avisar A. and Doljansky J. (2001) Enhancement of excessive lever-pressing after post-training signal attenuation in rats by repeated administration of the D1 antagonist SCH 23390 or the D2 agonist quinpirole but not of the D1 agonist SKF 38393 or the D2 antagonist haloperidol. Behavioral Neuroscience, 115, 1291–1300. PDF
13. Joel D., and Avisar A. (2001) Excessive lever pressing following post-training signal attenuation in rats:  A possible animal model of obsessive compulsive disorder? Behavioural Brain Research, 123, 77-87. PDF
12. Inzelberg R., Nisipeanu P., Joel D., Sarkantyus M., Blumen S.C., Carasso R.L. (2001) Acute mania and hemichorea. Clinical Neuropharmacology,  24, 300-303. Abstract
11. Joel D. and Weiner I. (2000) The connections of the dopaminergic system with the striatum in rats and primates: An analysis with respect to the functional and compartmental organization of the striatum. Neuroscience,  96, 451-474. PDF
10. Weiner I., Gaisler I., Shiller D., Green A., Zuckerman L. and Joel D. (2000) Screening of antipsychotic drugs in animal models. Drug Development Research, 50: 235-249. PDF
9. Weiner I., Feldon J., Tarrasch R., Hairston I., and Joel D. (1998) Fimbria-fornix cut affects spontaneous activity, two-way avoidance and delayed non matching to sample, but not latent inhibition. Behavioural Brain Research, 96, 59-70. PDF
8. Weiner I., Hairston I., Shayit M., Feldman G., Joel D., and Feldon J. (1998) Strain differences in latent inhibition. Psychobiology, 26, 57-64. PDF
7. Joel, D., Ayalon L., Tarrasch R., Zohar O., Veenman L., Feldon J., and Weiner, I. (1998) Electrolytic lesion of globus pallidus ameliorates the behavioral and neurodegenerative effects of quinolinic acid lesion of the striatum: A potential novel treatment in a rat model of Huntington’s disease. Brain Research, 787, 143-148. PDF
6. Joel, D., Tarrasch R., Feldon J., and Weiner, I. (1997) Effects of electrolytic lesions of the medial prefrontal cortex or its subfields on 4-arm baited 8-arm radial maze, two-way active avoidance and conditioned fear tasks in the rat. Brain Research, 765, 37-50. PDF
5. Joel D., Weiner, I., and Feldon J. (1997) Electrolytic lesions of the medial prefrontal cortex in rats disrupt performance on an analog of the Wisconsin Card Sorting Test but do not disrupt  latent inhibition: Implications for animal models of schizophrenia. Behavioural Brain Research, 85, 187-201. PDF
4. Joel, D., and Weiner, I. (1997) The connections of the primate subthalamic nucleus: Indirect pathways and the open-interconnected scheme of basal ganglia-thalamocortical circuitry. Brain Research Reviews, 23, 62-78. PDF

3. Gal, G., Joel, D., Gusak, O., Feldon, J., and Weiner, I. (1997) The effects of electrolytic lesion to the shell subterritory of the nucleus accumbens on delayed-non-match-to-sample and 4-arm baited 8-arm radial maze tasks. Behavioural Neuroscience, 111, 92-103. PDF
2. Gray, J. A., Joseph, M. H., Hemsley, D. R., Young, A. M. J., Warburton, E. C., Boulenguez, P., Grigoryan, G. A., Peters, S. L., Rawlins, J. N. P., Tai,  C.-T., Yee, B. K., Cassaday, H., Weiner, I., Gal, G., Gusak, O., Joel, D., Shadach, E., Shalev, U., Tarrasch, R., & Feldon, J. (1995) The role of mesolimbic dopaminergic and retrohippocampal afferents to the nucleus accumbens in latent inhibition: implications for schizophrenia.  Behavioural Brain Research, 71, 19-31. PDF
1.  Joel, D. and Weiner, I.  (1994) The organization of the basal ganglia-thalamocortical  circuits: Open-interconnected rather than closed segregated.  Neuroscience, 63, 363-379. PDF 

CHAPTERS IN BOOKS
4. Joel, D. (2014) Sex, Gender, and Brain – A Problem of Conceptualization. In S. Schmitz and G. Höppner (Eds). Gendered Neurocultures. Feminist and Queer Perspectives on Current Brain Discourses. Vienna: Zaglossus. e.U.
3. Joel D., Stein D.J. and Schreiber R. (2008) Animal Models Of Obsessive-Compulsive Disorder: From Bench To Bedside Via Endophenotypes And Biomarkers. In: R.A. McArthur and F. Borsini  (Eds). Animal and translational models of psychiatric disorders. Elsevier. HTML
2. Weiner I. and Joel D. (2002) Dopamine in schizophrenia: Dysfunctional information processing in basal ganglia-thalamocortical split circuits. In: Handbook of Experimental Pharmacology Vol. 154/II, Dopamine in the CNS II  (Ed. G. Di Chiara) Springer-Verlag, Berlin, pp. 417-472. PDF
1. Joel D. and Weiner I. (1999) Striatal contention scheduling and the split circuit scheme of basal ganglia-thalamocortical circuitry: From anatomy to behaviour. In: R. Miller and J.R. Wickens (Eds). Conceptual Advances in Brain Research: Brain dynamics and the striatal complex. Harwood Academic Publishers. Amsterdam. pp. 209-236. HTML 

OTHER PUBLICATIONS
7. Joel D. and Tarrasch R. (2014) On the mis-presentation and misinterpretation of gender-related data: The case of Verma’s human connectome study. PDF
6. Joel D. and Tarrasch R. (2010) The risk of a wrong conclusion – on testosterone and gender differences in risk aversion and career choices. Proc Natl Acad Sci USA, 107, E19 PDF
5. Niv Y., Dayan P. and Joel D. (2006) – The effects of motivation on extensively trained behavior – Leibniz Technical Report, Hebrew University, 2006-6. PDF
4. Joel D. (2002) Deep brain stimulation in Huntington’s disease – Globus pallidus externus or substantia nigra pars compacta. Movement Disorders, 17, 431-432. PDF
3. Niv Y., Joel D., Meilijson I. and Ruppin E. (2002) Evolution of reinforcement learning in foraging bees: a simple explanation for risk averse behavior. Neurocomputing 44-46, 951-956. PDF
2. Niv Y., Joel D., Meilijson I. and Ruppin, E. (2001) Evolution of reinforcement learning in uncertain environments: Emergence of risk aversion and probability matching. In J. Kelemen & P. Sosik (Eds.), Advances in Artificial life, Proceedings of ECAL’2001 – the 6th European Conference on Artificial Life, Springer-Verlag, pp. 252-261. PDF
1. Joel D. (1999) The limbic basal-ganglia-thalamocortical circuit and goal-directed behavior. Behavioral and Brain Sciences,  22, 525-526. HTML